Technology now available for Aseptic Processing The ChargePoint® BIO aseptic transfer valve sets new standards for the safe and clean transfer of sensitive product from process to process. A unique approach to bio-decontamination ensures the integrity of the critical sealing area. This unique technology resolves the contamination issues related to the brief time prior to docking when the mating surfaces of a valve are exposed to the production environment.
Technology now available for Aseptic Processing
The ChargePoint® BIO aseptic transfer valve sets new standards for the safe and clean transfer of sensitive product from process to process. A unique approach to bio-decontamination ensures the integrity of the critical sealing area. This unique technology resolves the contamination issues related to the brief time prior to docking when the mating surfaces of a valve are exposed to the production environment.
Now with ChargePoint® Bio you can achieve...
Aseptic batch transfers in a class D area.
A unique method of achieving a Grade A area within the valve itself eliminates the need for the construction of Grade A areas in new plants and enables aseptic transfers within lower class rooms in existing production areas.
Increased sterility confidence.
Utilizing ChargePoint® split valve technology offers a closed aseptic process which will limit manual handling and intervention. The valve can also be steam sterilized in place.
Repeatable batch transfers.
It is possible to perform multiple, repeated transfers, without the need for continuous SIP steps or re-validation. This makes the ChargePoint® BIO suitable for small or large scale and single batch or continuous processes.
High containment option.
The ChargePoint® BIO-EXCEL version will also provide nanogram level containment performance when handling potent sterile products.
Issues with alternative methods of sterile transfer: • There is a brief time prior to the docking of the transfer device during which the mating faces (or in worst cases product itself) is exposed to the operating environment – potentially becoming contaminated in the process. • Validation and cost of constructing areas with high classification. • Ring of concern’ when using valve technology. • Cost of isolator or laminar flow technology.
Issues with alternative methods of sterile transfer:
• There is a brief time prior to the docking of the transfer device during which the mating faces (or in worst cases product itself) is exposed to the operating environment – potentially becoming contaminated in the process.
• Validation and cost of constructing areas with high classification.
• Ring of concern’ when using valve technology.
• Cost of isolator or laminar flow technology.
Diagram of the ChargePoint BIO
The entry level ChargePoint® valve has long been used in aseptic processes, by utilizing the ability to SIP (Steam In Place) the Active unit prior to the transfer of product through the valve. The unique design of the Active unit allows a SIP Passive to be docked which enables the valve to be opened during sterilization. A pressure seal is maintained by an o-ring seal on the outer perimeter of the SIP Passive. Steam is then introduced typically at 1.5Bar at 125DegC. This assures the sterilization of not only the disc faces but also the disc edge. The ChargePoint® BIO valve operates according to the Split Butterfly Valve principle with an additional critical step for bio-decontamination. For diagrams of each step of the process please download the 'ChargePoint BIO Operation' document below.
The entry level ChargePoint® valve has long been used in aseptic processes, by utilizing the ability to SIP (Steam In Place) the Active unit prior to the transfer of product through the valve. The unique design of the Active unit allows a SIP Passive to be docked which enables the valve to be opened during sterilization. A pressure seal is maintained by an o-ring seal on the outer perimeter of the SIP Passive.
Steam is then introduced typically at 1.5Bar at 125DegC. This assures the sterilization of not only the disc faces but also the disc edge.
The ChargePoint® BIO valve operates according to the Split Butterfly Valve principle with an additional critical step for bio-decontamination. For diagrams of each step of the process please download the 'ChargePoint BIO Operation' document below.
Cleaning and Washing In Place (CIP / WIP / SIP) The ability to effectively clean or wash the product contact and sealing areas of a ChargePoint® valve is assured with the use of our specifically designed Wash In Place (WIP) devices. For ultra clean processing the valve can also be Steamed In Place (SIP).
Cleaning and Washing In Place (CIP / WIP / SIP)
The ability to effectively clean or wash the product contact and sealing areas of a ChargePoint® valve is assured with the use of our specifically designed Wash In Place (WIP) devices. For ultra clean processing the valve can also be Steamed In Place (SIP).
Automation & Docking Lifting and docking systems can be incorporated in-line with your material handling requirements.
Automation & Docking
Lifting and docking systems can be incorporated in-line with your material handling requirements.
Accessories A range of devices are available to enhance the performance, lifetime and usability of ChargePoint® containment valves.
Accessories
A range of devices are available to enhance the performance, lifetime and usability of ChargePoint® containment valves.