ChargePoint PharmaSafe® for Large Volume Transfers

PS Valve Key Brand DL

Containment Valves for Large Volume Powder Transfer

ChargePoint PharmaSafe® valves for large scale transfers ensure the safer handling of Highly Potent Active Pharmaceutical Ingredients (HPAPI) and other formulation ingredients. View our latest technical overview video below:


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ChargePoint PharmaSafe® Large Volume Transfer Valves

  • Dimaeters of 6" up to 10" (DN150-DN250) for large volume powder transfers
  • Safer handling of non-sterile API and formulation ingredients with the world's leading containment technology
  • Nanogram level containment performance

Contained filling and dispensing for all production processes from R&D to full scale production







Vessel Charging
Filtration / Separation
Wet/Dry Granulation
Blending / Mixing
Formulated blends
Raw materials
Tablets / Capsules


ChargePoint PharmaSafe® Large Valve Specifications

Pharmasafe Specifications Large


Containment Performance

ChargePoint PharmaSafe® valve containment performance has been independently validated by customers and third parties according to the ISPE SMEPAC (Standardised Measurement of Equipment Particulate Airborne Contamination) guideline.

Pharmasafe Containment Chart 01

Lifting and docking systems can be incorporated to ensure safe operation in hazardous or inaccessible areas or where the production scale does not permit manual handling:

• Fully or partially automated versions can be provided to suit application

• Status information and sequence interlocking, secured with the use of pneumatic or electric proximity sensors

• Fully integrated and factory tested control systems

• Repeatable and safe alignment of equipment in conjunction with lifting hoists and docking systems

• Reduced weight versions

• GMP covers to protect the valve while not in use


Learn more about Handling & Docking

Handling & Docking Accessories


Valve Automation

Wherever possible the ChargePoint® design offers the option of manual operation or partial automation versus full automation, reducing the cost and complexity of control systems. Larger diameter PharmaSafe valves can also be operated manually.



Pneumatic or electric proximity detection sensors, combined with existing mechanical safety interlock features ensure the safe function of the valve system.

Download the PharmaSafe® Brochure

PDF 710 01ChargePoint PharmaSafe® Brochure


PharmasafeChargePoint PharmaSafe®down to 1µg/m3

High containment performance with no additional seals, vacuum or extraction required.

The entry level ChargePoint PharmaSafe® offers a simple, cost effective upgrade to facilitate the required GMP and containment requirements in manufacturing. The minimum part design is easy to operate, clean and maintain whilst providing outstanding entry level performance.



Pharmasafe PlusChargePoint PharmaSafe® plus - down to <0.7µg/m3

Economic upgrade to existing installations or a modular unit in facilities with multiple ChargePoint® valves.

The ChargePoint PharmaSafe® plus extraction ring couples to the active unit and is connected to an extraction source.
High volume extraction during undocking ensures that airborne particulates are safely captured in the extracted air stream.


Pharmasafe Pro ChargePoint PharmaSafe® pro - down to 0.1µg/m3

High containment performance with a simple, low volume extraction.

The ChargePoint PharmaSafe® pro utilises an extraction process which is integral to the valve, to minimise the level of airborne contamination during the valve undocking sequence. The extraction requirement is designed to be adaptable with existing onsite air handling systems.



Pharmasafe ExcelChargePoint PharmaSafe® excel - <0.1 µg/m3

Advanced performance to nanogram levels in a compact efficient split valve.

The ChargePoint PharmaSafe® excel incorporates a simultaneous purge and extract sequence. During the undocking step a sealed cavity is created between the Active and Passive interface. The purge and extraction process is synchronised to remove traces of particles that can potentially become airborne once the valve is fully undocked.