As an industry, we have relied on high grade cleanroom environments to provide safe conditions to perform pharmaceutical material transfers in and out of process equipment. As a result, cleaning and disinfection has become increasingly scrutinised over the years.
ChargePoint Technology’s split butterfly valve (SBV) provides a contained method of transferring powders and products from one container or process vessel, to another, whilst minimising the levels of emission to the operating environment. Although we are no longer dependent on cleanroom environments for sterility assurance, aseptic SBVs require a bio decontamination step before material is transferred through the process and before any powder contact with the valve surface.
ChargePoint have written the following article discussing the sterilisation steps within a contained aseptic transfer system and the results in industry testing using a variation of bio decontamination materials.
Vaporized Hydrogen Peroxide (VHP) has been used for many years in the pharmaceutical industry, initially for cleanroom bio decontamination and then integrated into restricted access barrier systems (RABS) and isolators. Following our recent partnership with STERIS, we have collaborated to offer a unique and integrated solution for sterile powder transfer, a ‘dry’ technology process using VHP. VHP has since been adopted within ChargePoint’s aseptic SBV technology as the chosen substance for the decontamination the valve surfaces before any powder transfer takes place.
To view the full article and testing results, please download the article here
